The findings suggest that the molecule – known as an antisense oligonucleotide – potentially could treat neurodegenerative diseases characterized by abnormal tau, including Alzheimer’s.
“We’ve shown that this molecule lowers levels of the tau protein, preventing and, in some cases, reversing the neurological damage,” said Timothy Miller, MD, PhD, the David Clayson Professor of Neurology and the study’s senior author. “This compound is the first that has been shown to reverse tau-related damage to the brain that also has the potential to be used as a therapeutic in people.”
On behalf of all the loved ones suffering from a devasting neurological disease worldwide, in the St. Andrew’s Network, or here at home at Brooking Park, we send our full support and gratitude for your research.
This month, exclusive footage from a forthcoming PBS documentary Alzheimer’s: Every Minute Counts debuted on NextAvenue.org.
The clip focuses on tips offered by Dr. Rudolph Tanzi (Harvard Medical School) to reduce the spread of memory loss. His advice includes the usual suspects: maintaining a healthy diet, getting exercise, and (our favorite) getting 7-8 hours of deep sleep per night.
The Brooking Park team felt especially compelled to share this video in relation to our October post about the (in)effectiveness of popular brain games. Dr. Tanzi touches on this topic:
So I tell people, ‘when you’re getting ready for retirement, you have to equally think of a financial reserve, and a synaptic reserve’….And that really means learning new things. It doesn’t mean playing brain games, which could just help focus, but not really make new synapses
His analogy contrasts New York Times crossword puzzles from Monday through Thursday – which only helps focus, versus the weekend crosswords that require the solver to apply what they’ve learned during the week from the weekday puzzles.
Check out the four-minute video below:
The 60-minute documentary premiers January 25, 2017, at 9pm CST on PBS.
As a New Year’s resolution, challenge yourself: replace red meat with fish, find ways to reduce stress, and stay socially and intellectually active!